IPS Brazil – Internacional Proteolysis Society – A Meeting an Proteases , their Substrates and Inhibitors in Health and Disease

OCTOBER, 26 - 30TH, 2025

Atlântico Convention and Resort

Búzios, Rio de Janeiro – Brazil

A MEETING ON PROTEASES , THEIR SUBSTRATES AND INHIBITORS IN HEALTH AND DISEASE

Blood Disorders and Hemostasis
Cancer
Cardiovascular disease
Drug Discovery
Immunity
Metabolism and Metabolic Disorders
Neurodegenerative Disorders and Ageing

New Tools to Study Proteolysis
Pathogens
Signaling
Skin and wounding
Structure – Function Relationship
Ubiquitination and Protein turnover

Hotel Atlântico Búzios

Estr. da Usina Velha, 294
Village de Búzios, Búzios
RJ – Brazil

Organization

Chair: Ana Paula Lima – Universidade Federal do Rio de Janeiro
Co-Chair: Maria Luiza Oliva – Universidade Federal de São Paulo

INTERNATIONAL
Scientific Committee

Anthony O’Donoghue
University of California in San Diego
Laura Edgington-Mitchell
University of Melbourne
Marcin Drag
Wroclaw University of Technology
Ruth Geiss-Friedlander
University of Freiburg
Thomas Reinheckel
University of Freiburg

LOCAL
Scientific Committee

Ana Marisa Chudzinski-Tavassi
Instituto Butantan
Heloisa Sobreiro Selistre de Araújo
Universidade Federal de São Carlos
Patrícia Maria Guedes Paiva
Universidade Federal de Pernambuco

Event of:

Sponsorship:

Organization support:

General Information

The International Proteolysis Society aims to promote knowledge on the role of proteolysis in all aspects of biological and biomedical research, assembling a wide audience of experts and promoting the training of young scientists in the field. The biennial Meeting of IPS brings together the global scientific community working on proteases, their substrates, and inhibitors, and is a must attend event since 1999.

Highlighted themes include: ageing, cancer, protein turnover and degradation, blood, immunity, infections, neurobiology, metabolism, therapeutic targets, structural biology and much more!

The conference will bring together researchers at various career stages and industry representatives across the field of proteolysis. The 5-day event will include the latest developments in basic and translational research involving proteases including cell biology, structure, biochemistry, new therapeutic approaches for human diseases and state of the art technologies.

IPS2025 will represent a key opportunity for interaction across borders and research fields to enhance knowledge in proteolysis in biological and biomedical sciences, providing exciting opportunities for international collaboration.

IPS2025 will be held in the coastal town of Armação dos Búzios, situated in the State of Rio de Janeiro, in Brazil, just 173 km from the international airport of the city of Rio de Janeiro. Búzios is a beautiful tourist village, located in the tropical zone of the South American subcontinent, bathed by the waters of the Atlantic Ocean, with 23 beaches.

VISA REQUIREMENTS: Brazil requires entry visas for citizens of Afghanistan, Algeria, Angola, Australia Bhutan, Cambodia, Canada, Chad, China, Comoros, Cuba, Democratic Republic of Congo, Djibouti, Egypt, Equatorial Guinea, Eritrea, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Haiti, Ivory Coast, India, Iraq, Iran, Jordan, Kazakhstan, Kenya, Kyrgyzstan, Laos, Lesotho, Liberia, Libya, Madagascar, Malawi, Maldives, Mali, Morocco, Mauritania, Mozambique, Nepal, Niger, Nigeria, North Korea, Oman, Pakistan, Republic of Congo, Rwanda, Saudi Arabia, Senegal, Sierra Leone, Somalia, Sri Lanka, Sudan, South Sudan, Taiwan, Tanzania, Togo, Uganda, United States of America, Uzbekistan, Vanuatu, Vietnam, Yemen, Zambia, Zimbabwe.

Please check if you require a visa at:
https://formulario-mre.serpro.gov.br/sci/pages/web/ui/#/servicos-estrangeiros

Be aware that visas may take a few weeks to be issued, so apply early. Note the change in Brazilian Law effective April 10th, 2025 that will also require US, Canadian and Australian citizens to apply for visas prior to entry.

If you need a letter for your visa application, please send a request with your full name to: ipsbrazil2025@gmail.com

We look forward to welcoming you to IPS2025 in Búzios!

CHECK LATER FOR UPDATES IN THE FULL PROGRAM

Plenary Speakers:
Opening Lecture: Dr. Vishva Dixit (Genentech – USA)
Prof. Thomas Langer (Max Planck Institute for Biology of Ageing – Germany)
Prof. Irit Sagi (The Weizmann Institute of Science – Israel)
Prof. Matthew Bogyo (Stanford University – USA)

Confirmed Speakers:
Solange Serrano – Instituto Butantan
Natalie Sims – St Vincent’s Institute Melbourne – Australia
Dieter Brömme – University of British Columbia – Canada
Taisuke Tomita – University of Tokyo – Japan
Malte Gersch- Chemical Genomics Center Max Planck Society – Germany
Wioletta Rut – Wroclaw University – Poland
Joanne Lemieux – University of Alberta – Canada
Jonas Emsley – University of Nottingham – United Kingdom
Hans Brandstetter – University of Salzburg – Austria
Ruth Geiss-Friedlander – University of Freiburg – Germany
Thomas Reinheckel – University of Freiburg – Germany
William Bachovchin – Tufts University – USA
Anthony O’Donoghue – University of California San Diego – USA
Galia Blum – The Hebrew University of Jerusalem – Israel
Konstantinos Kalogeropoulos – Technical University of Denmark
Ze Zheng – University of Wisconsin Medical College – USA
Long-Sheng Song – University of Iowa – USA
Brice Korkmaz – INSERM- France
Kuan-Ju Chen – INSMED – USA
Lada Sabirova – INSERM – France
Christopher Overall – University of British Columbia – Canada
Laura Edgington-Mitchell – University of Melbourne – Australia
Nathan Archer – The Johns Hopkins University – USA
Natalie Vergnolle – INSERM – France
Catherine Moali – CNRS – France
Mark Gorrell – University of Sidney – Australia
Guy Salvesen – Sanford-Burnham Medical Research Institute – USA
Hayley Newton – Monash University – Australia
Jeremy Mottram – University of York – United Kingdom
Marcio Lourenço Rodrigues – FIOCRUZ – Brasil
Manuel Saldivia – Novartis – USA
Henry Maun – Genentech – USA
Rama Khokha – University of Toronto
Patrick McDonald – INSMED
Izabela Borek- Ludwig Boltzan Institute – Austria

Lifetime Achievement Award Recipients:
Luiz Juliano – UNIFESP- Brasil
Robert Lazarus – Genentech – USA

October 26th:
16:00h-18:00h: Registration
18:45h-19:15h – Opening Ceremony (IPS 25th anniversary)
19:15-20:00h – Opening Lecture
20:00h-22:00h – Welcome reception

October 27th:
9:00-10:00h – Plenary Lecture
10:00-10:25h – Coffee Break
10:30h-11:45h – Session 1
11:45h-12:15h – Oral presentations selected from abstracts
12:15h-13:50h – Lunch
14:00h-15:15h – Session 2
15:15h-15:40h – Oral presentations selected from abstracts
15:40h-16:10h – Coffee break
16:15h-17:35h – Session 3
17:35h-18:00h – Oral presentations selected from abstracts
18:00-19:30h – Poster Session 1

October 28th:
9:00-10:00h – Plenary Lecture
10:00-10:25h – Coffee Break
10:30h-11:45h – Session 4
11:45h-12:15h – Oral presentations selected from abstracts
12:15h-13:50h – Lunch
14:00h-15:15h – Session 5
15:15h-15:40h – Oral presentations selected from abstracts
15:40h-16:10h – Coffee break
16:15h-18:00 h – Session 6
18:00-19:30h – Poster Session 2

October 29th:
8:00h-9:30h – Special session: “Pharmacological Inhibition of Cathepsin C (Dipeptidyl Peptidase 1) in Neutrophil-Mediated Diseases”
9:30h-12:15h – Free Morning
12:15h-13:50h – Lunch
14:00h-15:40h – Session 7
15:40h-16:10h – Coffee break
16:15h-17:35 h – Session 8
17:35h-18:00h – Young Investigator Award Lecture
18:00h-19:30h – IPS Members Business Meeting/Election

October 30th:
9:00-10:00h – Plenary Lecture
10:00-10:25h – Coffee Break
10:30h-11:45h – Round Table 9
11:45h-12:15h – Oral presentations selected from abstracts
12:15h-13:50h – Lunch
14:00h-15:40h – Round Table 10
15:40h-16:10h – Coffee break
16:15h-17:05h – Lifetime Achievement Award Lecture 1: Luiz Juliano- UNIFESP
17:05h-17:55h – Lifetime Achievement Award Lecture 2: Robert Lazarus – Genentech
18:00-19:15h: IPS Young Investigator Award / Poster Awards / Travel Awards; IPS 2027 Vennue – Closing Remarks
20:00h: Banquet Dinner (not included in the registration fee)